---
title: "Serum Uric Acid Optimal Range vs Lab Normal (2026 Clinical Decoder & Protocol) | Nutrition Research Labs"
source_url: "https://nutritionresearchlabs.com/biomarkers/uric-acid"
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description: "Decode your Serum Uric Acid (Uric Acid) blood test: Longevity Optimal Target (3.5–5.2 mg/dL) vs Standard Lab Normal (3.5–7.2 mg/dL), assay interference, and Grade-A clinical protocols."
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> **Canonical Source:** [https://nutritionresearchlabs.com/biomarkers/uric-acid](https://nutritionresearchlabs.com/biomarkers/uric-acid)
>
> *Decode your Serum Uric Acid (Uric Acid) blood test: Longevity Optimal Target (3.5–5.2 mg/dL) vs Standard Lab Normal (3.5–7.2 mg/dL), assay interference, and Grade-A clinical protocols.*

## Reference Range Comparison (mg/dL)

- **Longevity & Metabolic Optimal Range:** 3.5 – 5.2 mg/dL
- **Standard Lab Reference Interval ("Normal"):** 3.5 – 7.2 mg/dL
- **Why Standard Lab Ranges Mislead Patients:** Labs only flag uric acid above 7.0-7.2 mg/dL based on the physical solubility threshold for sodium urate crystallization (gout). Cardiometabolic studies show intracellular endothelial dysfunction and renal afferent arteriolopathy escalate above 5.5 mg/dL.
- **Pre-Draw Supplement Assay Interference Warning:** High-dose Vitamin C (>2g/day) or salicylate ingestion enhances renal uricosuric clearance, falsely lowering serum uric acid. Severe ketosis or lactic acidosis competes for renal URAT1 transporters, transiently raising serum uric acid.

## Decode the Next Biomarker on Your Blood Panel

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