---
title: "De Ritis Ratio (AST/ALT Transaminase Ratio) Optimal Range vs Lab Normal (2026 Clinical Decoder & Protocol) | Nutrition Research Labs"
source_url: "https://nutritionresearchlabs.com/biomarkers/ast-alt-de-ritis-ratio"
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description: "Decode your De Ritis Ratio (AST/ALT Transaminase Ratio) (AST/ALT Ratio) blood test: Longevity Optimal Target (0.8–1.1 Ratio) vs Standard Lab Normal (0.7–1.5 Ratio), assay interference, and Grade-A clinical protocols."
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> **Canonical Source:** [https://nutritionresearchlabs.com/biomarkers/ast-alt-de-ritis-ratio](https://nutritionresearchlabs.com/biomarkers/ast-alt-de-ritis-ratio)
>
> *Decode your De Ritis Ratio (AST/ALT Transaminase Ratio) (AST/ALT Ratio) blood test: Longevity Optimal Target (0.8–1.1 Ratio) vs Standard Lab Normal (0.7–1.5 Ratio), assay interference, and Grade-A clinical protocols.*

## Reference Range Comparison (Ratio)

- **Longevity & Metabolic Optimal Range:** 0.8 – 1.1 Ratio
- **Standard Lab Reference Interval ("Normal"):** 0.7 – 1.5 Ratio
- **Why Standard Lab Ranges Mislead Patients:** Labs report AST and ALT individually without calculating their ratio. A patient with AST 22 and ALT 44 appears entirely normal on standard panels, yet their ratio of 0.50 clearly indicates significant steatosis and hepatic metabolic distress.
- **Pre-Draw Supplement Assay Interference Warning:** Severe hemolysis falsely spikes AST dramatically because erythrocytes contain roughly 40 times higher AST concentrations than plasma.

## Decode the Next Biomarker on Your Blood Panel

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