---
title: "Alanine Aminotransferase (ALT Liver Transaminase) Optimal Range vs Lab Normal (2026 Clinical Decoder & Protocol) | Nutrition Research Labs"
source_url: "https://nutritionresearchlabs.com/biomarkers/alt-alanine-aminotransferase"
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description: "Decode your Alanine Aminotransferase (ALT Liver Transaminase) (ALT (SGPT)) blood test: Longevity Optimal Target (10–24 U/L) vs Standard Lab Normal (7–56 U/L), assay interference, and Grade-A clinical protocols."
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> **Canonical Source:** [https://nutritionresearchlabs.com/biomarkers/alt-alanine-aminotransferase](https://nutritionresearchlabs.com/biomarkers/alt-alanine-aminotransferase)
>
> *Decode your Alanine Aminotransferase (ALT Liver Transaminase) (ALT (SGPT)) blood test: Longevity Optimal Target (10–24 U/L) vs Standard Lab Normal (7–56 U/L), assay interference, and Grade-A clinical protocols.*

## Reference Range Comparison (U/L)

- **Longevity & Metabolic Optimal Range:** 10 – 24 U/L
- **Standard Lab Reference Interval ("Normal"):** 7 – 56 U/L
- **Why Standard Lab Ranges Mislead Patients:** Historic laboratory reference ranges extended up to 55-60 U/L because reference cohorts included undiagnosed non-alcoholic fatty liver disease (NAFLD). Updated hepatology guidelines established that healthy upper limits are 19-25 U/L for women and 25-30 U/L for men.
- **Pre-Draw Supplement Assay Interference Warning:** Strenuous muscular resistance training within 72 hours releases minor amounts of transaminases from skeletal muscle. Severe Vitamin B6 deficiency artificially suppresses measured ALT activity in pyridoxal-dependent assays.

## Decode the Next Biomarker on Your Blood Panel

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